P110 ( —— )

产品货号. M30578 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

P110
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen species (ROS) production in vitro. Reduces programmed cell death and improves cell viability by protecting mitochondrial integrity. Reduces mitochondrial fragmentation and mitochondrial ROS production in mouse model of Parkinson's disease. Cell permeable.
产品描述

Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen species (ROS) production in vitro. Reduces programmed cell death and improves cell viability by protecting mitochondrial integrity. Reduces mitochondrial fragmentation and mitochondrial ROS production in mouse model of Parkinson's disease. Cell permeable.
体外实验

——
体内实验

——
同义词

——
通路

Others
靶点

Other Targets
受体

——
研究领域

——
适应症

——

CAS Number

——
分子量

2411.8
分子式

C100H179N45O25
纯度

>98% (HPLC)
溶解度

water:1 mg/mL
SMILES

[H]N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(NCC(N[C@H](C(N)=O)CO)=O)=O)CCCNC(N)=N)=O)=O)CC(C)C)=O)CC(C)C)=O)CC(O)=O)=O)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CC2=CC=C(C=C2)O
化学全称

——

1. Qi et al (2013) A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. J.Cell Sci. 126 789 PMID:

计算器

产品手册

关联产品

Braylin

Braylin has anti-inflammatory, antinociceptive and immunomodulatory effects, which possibly act through the glucocorticoid receptor activation and by inhibition of the transcriptional activity of NF-κB.
20-O-Acetylingenol-3...

20-O-Acetylingenol-3-angelate 是来自 Euphorbia lathyris L 的天然化合物。
11-Oxomogroside IIe

11-Oxomogroside IIe 是从罗汉果中分离得到的天然萜糖苷类化合物。